Nov 18

Legemiddelfirmaet Pfizer: Forskningsjuks i stor stil

Wed, 11/18/2009 - 19:01 — F.R.R.

 
Et av verdens største legemiddelfirmaer, Pfizer, er avslørt i enormt juks med forskningsresultater. Det dreier seg om legemiddelet Neurontin, et middel mot epilepsi, men som firmaet markedsfører også for andre tilstander. Kun 12 av 20 forskningsrapporter er offentliggjort, og av disse er 8 manipulert for å få "ønskede" resultater.

Firmaet har markedsført prepararet mot perifere nervesmerter, samt i noen tilfeller også muskesmerter, migrene og schizofreni. En kritisk gjennomgang av de opprinnelige forskningsprotokollene konkluderer med at legemiddelet egentlig bare har dokumentert effekt på epilepsi. Jukset har skjedd både ved tilbakeholdelse av uønskede resultater, samt fiksing både av resultater og statistiske mål. 

»Det er længe siden jeg har læst en så etisk bekymrende rapport,« sagde Arthur Caplan, direktør for Center for Bioetik ved Universitetet i Pennsylvania, USA, i en kommentar, og den danske ekspert Asbjørn Hrobjartsson fra Cochrane Centret er meget enig: 

»Vi står over for et kæmpe problem, og det kan ikke gå hurtigt nok med at gøre det lovpligtigt at offentliggøre alle protokoller.«

- Ingeniøren.dk

Firmaet har nylig fått en bot på svimlende 2,3 milliarder dollar for ulovlig markedsføring i USA. Pfizer selv avviser kritikken, og mener den fremlagte rapporten ikke holder vitenskapelig mål.

Firmaet står også bak prepararet Lyrica, neste generasjon av stoffet i Neurontin. 

 

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